Why Infection Navigator?
Deterministic Clinical Decision Support
Bypasses generalized LLM hallucinations in favor of a 100% rule-based, deterministic clinical evaluation engine aligned strictly with IDSA, CDC STI, and AAO-HNS guideline algorithms.
Patient-Specific Safety & Dosing Filters
Instantly adapts empiric and culture-guided regimens to individual patient baseline parameters, screening in real time for renal dose adjustments (eGFR), beta-lactam allergies, and pregnancy/lactation contraindications.
Zero PHI & 100% Client-Side Privacy
Engineered entirely client-side within the browser. Zero patient health information (PHI) is ever transmitted, logged, or stored on external servers, ensuring seamless compliance with clinical privacy standards.
Clinical Workflow: 4-Stage Antimicrobial Stewardship Architecture
Stage 1: Multi-Modal Presentation & Diagnostic Triage
- Four Diagnostic Entry Points: Evaluate cases by presenting symptom complexes, confirmed clinical diagnoses, isolated microbiological organisms, or formal culture & susceptibility (C&S) reports.
- Rapid Syndrome Access: One-click triage for high-volume outpatient syndromes including uncomplicated cystitis, pyelonephritis, comprehensive STIs (chlamydia, gonorrhea, syphilis, primary/recurrent/suppressive HSV), Centor-scored pharyngitis, ABRS, and community-acquired pneumonia.
- Active Diagnostic Criteria Screening: Interactive questionnaire systematically screens for red flags, complicated illness indicators, and antibiotic stewardship criteria before generating recommendations.
Stage 2: Deterministic Safety & Contraindication Filtering
- Dynamic Baseline Safety Profiling: Integrates age, biological sex, pregnancy status, and real-time eGFR thresholds.
- Cross-Reactivity & Allergy Intelligence: Differentiates true anaphylaxis/IgE-mediated beta-lactam reactions from mild intolerances, automatically substituting safe alternatives or desensitization advisories.
- Antimicrobial Stewardship Safeguards: Promotes first-line narrow-spectrum agents while actively discouraging inappropriate fluoroquinolone or broad-spectrum cephalosporin utilization for self-limiting viral syndromes.
Stage 3: Evidence-Based Regimen Selection & Suspension Engine
- Guideline-Concordant First-Line & Alternative Regimens: Provides explicit drug dosing, delivery route, frequency, and exact duration.
- Formulation & Weight-Based Precision: Automatically computes pediatric and adult weight-tiered dosing (including ceftriaxone dosing cutoffs at 150 kg for gonorrhea) with standard commercial suspension concentrations.
- Resistance Pattern Warnings: Flags high community resistance thresholds (e.g., local E. coli TMP-SMX resistance >20%, fluoroquinolone-resistant campylobacter, and macrolide-resistant mycoplasma).
Stage 4: Point-of-Care Documentation & Actionable Discharge
- EHR-Ready Medical Decision Making (MDM): Instantly exports structured dotphrases documenting diagnostic scoring, stewardship rationale, and contraindication screening for clinical audit compliance.
- Patient-Facing Instructions: Generates plain-language counseling points covering administration timing, food/mineral binding interactions (calcium, iron, antacids), photosensitivity, and red-flag return precautions.
How to Use Infection Navigator in Practice
- Confirm or Edit Patient Safety Baseline: Verify the patient snapshot at the top of the workspace (Age, Biological Sex, eGFR, Allergies, Pregnancy/Lactation) to ensure all contraindication filters reflect the active clinical encounter.
- Select Clinical Entry Point or Syndrome: Select an evaluation pathway via the top navigation tabs (Symptoms, Diagnosis, Organism, Culture) or choose an outpatient presentation directly from Quick Access.
- Complete the Focused Screening Questionnaire: Answer the sequential clinical evaluation queries to objectively evaluate diagnostic criteria, identify complicating features, and rule out viral etiologies.
- Review Deterministic Recommendation: Inspect the resulting primary first-line regimen, evidence-based alternatives, renal adjustments, and clinical monitoring guidance generated by the engine.
- Export Clinical Documentation: Use the one-click copy tool to paste the billing-compliant MDM note directly into your EHR progress note and provide the patient care instructions at discharge.
